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One or more keywords matched the following properties of Stephens, Matthew
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overview My lab works on a wide variety of problems at the interface of Statistics and Genetics. We often tackle problems where novel statistical methods are required, or can learn something new compared with existing approaches. Thus, much of our research involves developing new statistical methodology, many of which have a non-trivial computational component. People in my lab tend to come from a quantitative background (e.g., Statistics, Computer Science), with varying levels of formal or informal Biology training.
One or more keywords matched the following items that are connected to Stephens, Matthew
Item TypeName
Concept Genetics, Behavioral
Concept Genetics, Medical
Concept Genetics, Population
Concept Quantitative Trait, Heritable
Concept Quantitative Trait Loci
Academic Article Inference of population structure using multilocus genotype data: linked loci and correlated allele frequencies.
Academic Article Traces of human migrations in Helicobacter pylori populations.
Academic Article The effects of genotype-dependent recombination, and transmission asymmetry, on linkage disequilibrium.
Academic Article Genome-wide detection and characterization of positive selection in human populations.
Academic Article Understanding mechanisms underlying human gene expression variation with RNA sequencing.
Academic Article Exon-specific QTLs skew the inferred distribution of expression QTLs detected using gene expression array data.
Academic Article Dissecting the regulatory architecture of gene expression QTLs.
Academic Article The contribution of RNA decay quantitative trait loci to inter-individual variation in steady-state gene expression levels.
Academic Article Mapping gene-environment interactions at regulatory polymorphisms: insights into mechanisms of phenotypic variation.
Academic Article DNase?I sensitivity QTLs are a major determinant of human expression variation.
Academic Article High-resolution mapping of expression-QTLs yields insight into human gene regulation.
Academic Article Genes mirror geography within Europe.
Academic Article Genetic, functional and molecular features of glucocorticoid receptor binding.
Academic Article A statistical framework for joint eQTL analysis in multiple tissues.
Academic Article Mangravite et al. reply.
Academic Article Insights into recombination from population genetic variation.
Academic Article Analysis of population structure: a unifying framework and novel methods based on sparse factor analysis.
Academic Article msHOT: modifying Hudson's ms simulator to incorporate crossover and gene conversion hotspots.
Academic Article Fast and accurate estimation of the population-scaled mutation rate, theta, from microsatellite genotype data.
Academic Article An estimate of the average number of recessive lethal mutations carried by humans.
Academic Article A statin-dependent QTL for GATM expression is associated with statin-induced myopathy.
Academic Article Imputation-based analysis of association studies: candidate regions and quantitative traits.
Academic Article The genetic architecture of gene expression levels in wild baboons.
Academic Article fastSTRUCTURE: variational inference of population structure in large SNP data sets.
Academic Article A comparison of phasing algorithms for trios and unrelated individuals.
Academic Article A comparison of bayesian methods for haplotype reconstruction from population genotype data.
Academic Article A fast and flexible statistical model for large-scale population genotype data: applications to inferring missing genotypes and haplotypic phase.
Academic Article Linkage disequilibrium-based quality control for large-scale genetic studies.
Academic Article Modeling linkage disequilibrium and identifying recombination hotspots using single-nucleotide polymorphism data.
Academic Article Visualizing spatial population structure with estimated effective migration surfaces.
Academic Article New evidence for hybrid zones of forest and savanna elephants in Central and West Africa.
Academic Article Flexible statistical methods for estimating and testing effects in genomic studies with multiple conditions.
Academic Article Genotyping Polyploids from Messy Sequencing Data.
Academic Article Estimating recent migration and population-size surfaces.
Academic Article Discovery and characterization of variance QTLs in human induced pluripotent stem cells.
Academic Article Characterizing and inferring quantitative cell cycle phase in single-cell RNA-seq data analysis.
Academic Article Genetic analyses support the contribution of mRNA N6-methyladenosine (m6A) modification to human disease heritability.
Academic Article Cell type-specific genetic regulation of gene expression across human tissues.
Academic Article The impact of sex on gene expression across human tissues.
Academic Article Dynamic effects of genetic variation on gene expression revealed following hypoxic stress in cardiomyocytes.
Grant Multipoint and significance methods for genome-wide association studies
Grant Statistical analysis of gene expression quantitative trait loci (eQTL)
Academic Article Adjusting for genetic confounders in transcriptome-wide association studies improves discovery of risk genes of complex traits.
Search Criteria
  • Quantitative
  • Genetics